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Article

Improved culture methods to expand schwann cells with altered growth behaviour from CMT1A patients

1 Jun 1998

Abstract excerpt

A duplication of the gene for myelin protein PMP22 is by far the most common cause of the hereditary demyelinating neuropathy CMT1A. A role for PMP22 in cell growth in addition to its function as a myelin protein has been suggested because PMP22 is homologous to a gene specifically upregulated during growth arrest. Furthermore, transfected rat Schwann cells overexpressing PMP22 show reduced growth. In addition,...

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Identifiers

PMID: 9600378
DOI: 10.1002/(sici)1098-1136(199806)23:2<89::aid-glia1>3.0.co;2-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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