Analysis of spinocerebellar ataxia type 2 in Gunma Prefecture in Japan: CAG trinucleotide expansion and clinical characteristics.

doi:10.1016/s0022-510x(98)00040-9

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Article

Analysis of spinocerebellar ataxia type 2 in Gunma Prefecture in Japan: CAG trinucleotide expansion and clinical characteristics.

Journal of the neurological sciences - 1 Apr 1998

Mizushima K, Watanabe M, Abe K, Aoki M, Itoyama Y, Shizuka M, Okamoto K, Shoji M

Abstract excerpt

We analyzed 13 patients with spinocerebellar ataxia type 2 (SCA2) in seven unrelated families who live in Gunma Prefecture, Japan (population approx. 2,000,000), and documented the clinical and molecular properties correlated with the CAG repeat expansion. Twelve of the 13 patients and one presym...

Topics

Adolescent
Adult
Child
Female
Humans
Japan
Magnetic Resonance Imaging
Male
Middle Aged
Phenotype
Spinocerebellar Degenerations
Trinucleotide Repeats

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