Article
Intersubunit interactions allowing a carboxylate mutant coat protein to inhibit tobamovirus disassembly.
Virology - 25 Apr 1998
Lu B, Taraporewala F, Stubbs G, Culver J N
Abstract excerpt
Tobacco mosaic tobamovirus (TMV) coat protein (CP) mutant E50Q lacks a repulsive intersubunit carboxylate group and can effectively inhibit the disassembly of wild-type TMV (Culver et al, 1995, Virology 206,724). To investigate the ability of this mutant CP to block disassembly, a series of second-site amino acid substitutions were added to the E50Q CP. These second-site mutations were designed to disrupt...
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