Article
Carboxylate interactions involved in the disassembly of tobacco mosaic tobamovirus.
Virology - 1 Nov 1996
Lu B, Stubbs G, Culver J N
Abstract excerpt
Structural studies of tobacco mosaic tobamovirus (TMV) have identified two coat protein (CP) intersubunit carboxyl-carboxylate interactions and one CP carboxylate-RNA phosphate interaction whose electrostatic repulsion is believed to drive virion disassembly. In this study, the involvement of each interaction in the disassembly process was examined. Site-directed mutagenesis was used to replace selected...
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