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Article

Progressive Telomere Shortening in Aplastic Anemia

15 May 1998

Abstract excerpt

Improved survival in aplastic anemia (AA) has shown a high incidence of late clonal marrow disorders. To investigate whether accelerated senescence of hematopoietic stem cells might underlie the pathophysiology of myelodysplasia (MDS) or paroxysmal nocturnal hemoglobinuria (PNH) occurring as a late complication of AA, we studied mean telomere length (TRF) in peripheral blood leukocytes from 79 patients with AA,...

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Share to Cytomegalovirus and herpesvirus research
Share to Hematopoietic Stem Cell Transplantation
Share to Telomeres, Telomerase, and Senescence

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Identifiers

PMID: 9572992
DOI: 10.1182/blood.v91.10.3582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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