Article
Risk estimates for dichotomous genetic disease traits based on a cohort study of relatedness in purebred dog populations.
The Veterinary record - 28 Mar 1998
Ubbink G J, van de Broek J, Hazewinkel H A, Rothuizen J
Abstract excerpt
As a result of strong selection in closed gene pools, dog breeds represent populations of highly related animals. Prominent founder-effects are responsible for inherited diseases occurring in particular breeds, and each breed may have several breed-related diseases, often with a high incidence. Such inherited diseases are a major problem in purebred dog populations, and probably threaten their survival. On the...
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