Article
Association between the gamma-aminobutyric acid A3 receptor gene and multiple sclerosis.
Archives of neurology - 1 Apr 1998
Gade-Andavolu R, MacMurray J P, Blake H, Muhleman D, Tourtellotte W, Comings D E
Abstract excerpt
BACKGROUND: In a prior study we observed an association between the dopamine D2 receptor gene (DRD2) and the age of onset and/or diagnosis of multiple sclerosis (MS). We hypothesized that this effect was mediated through the dopaminergic control of the release of prolactin, a modulator of immune response. Since gamma-aminobutyric acid also modulates the release of prolactin, we examined the possible association...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.