Article
RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phase.
Molecular microbiology - 1 Jun 2001
Bachman M A, Swanson M S
Abstract excerpt
Legionella pneumophila replicates within amoebae and macrophages and causes the severe pneumonia Legionnaires' disease. When broth cultures enter the post-exponential growth (PE) phase or experience amino acid limitation, L. pneumophila accumulates the stringent response signal (p)ppGpp and expresses traits likely to promote transmission to a new phagocyte. The hypothesis that a stringent response mechanism...
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