Article
[Human immunodeficiency virus and AIDS in terms of reverse transcriptase and molecular evolution].
Nihon rinsho. Japanese journal of clinical medicine - 1 Mar 1998
Doi H
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) evolves rapidly in the host. The computer analysis of the HIV-1 genome has shown that the mutation manner is dependent on oligonucleotide sequences (in particular, six bases long); thus HIV-1 adaptively evolves. The six-base-long interaction between tem...
Topics
- Acquired Immunodeficiency Syndrome
- Base Sequence
- Disease Progression
- Drug Resistance, Microbial
- Evolution, Molecular
- Genes, env
- Genome, Viral
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Mutation
- Oligonucleotides
