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Article

[Human immunodeficiency virus and AIDS in terms of reverse transcriptase and molecular evolution].

Nihon rinsho. Japanese journal of clinical medicine - 1 Mar 1998

Doi H

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) evolves rapidly in the host. The computer analysis of the HIV-1 genome has shown that the mutation manner is dependent on oligonucleotide sequences (in particular, six bases long); thus HIV-1 adaptively evolves. The six-base-long interaction between template-primer oligonucleotide and the reverse transcriptase (RT) has been revealed by the crystal structure of RT, in...

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PMID: 9549376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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