Article
Ontogenetic limb bone scaling in basic fibroblast growth factor (FGF-2) transgenic mice.
Growth, development, and aging : GDA - 1 Jan 2000
Lightfoot P S, Swisher R, Coffin J D, Doetschman T C, German R Z
Abstract excerpt
Basic fibroblast growth factor (FGF-2) is a potent mitogen which is required for normal development, particularly the development of the skeletal system, where the inhibition of FGF binding to its receptor results in various skeletal malformations. The present study employed a newly engineered li...
Topics
- Animals
- Anthropometry
- Body Weight
- Bone Development
- Data Interpretation, Statistical
- Female
- Femur
- Fibroblast Growth Factors
- Forelimb
- Genotype
- Hindlimb
- Humerus
- Male
- Mice
- Mice, Transgenic
- Organ Size
- Sex Factors
- Tibia