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Article

Ontogenetic limb bone scaling in basic fibroblast growth factor (FGF-2) transgenic mice.

Growth, development, and aging : GDA - 1 Jan 2000

Lightfoot P S, Swisher R, Coffin J D, Doetschman T C, German R Z

Abstract excerpt

Basic fibroblast growth factor (FGF-2) is a potent mitogen which is required for normal development, particularly the development of the skeletal system, where the inhibition of FGF binding to its receptor results in various skeletal malformations. The present study employed a newly engineered line of FGF-2 transgenic mice to determine the effects of overexpressing FGF-2 on limb bone ontogeny. We collected...

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PMID: 9546104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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