Article
Correlated heart/limb anomalies in Mendelian syndromes provide evidence for a cardiomelic developmental field.
American journal of medical genetics - 1 Apr 1998
Wilson G N
Abstract excerpt
Coordinated development of heart and limbs is suggested by a review of human abortus, chromosomal, and teratogenic syndromes, and characterized by an analysis of Mendelian disorders that affect the limbs, heart, or both (672, 202, or 107, respectively). Mendelian syndromes with altered limb patterns often include cardiac anomalies, as shown by limb duplications (34%), deficiencies (30%), hypoplasias (23%), or...
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