Correlated heart/limb anomalies in Mendelian syndromes provide evidence for a cardiomelic developmental field.

Article

Correlated heart/limb anomalies in Mendelian syndromes provide evidence for a cardiomelic developmental field.

American journal of medical genetics - 1 Apr 1998

Wilson G N

Abstract excerpt

Coordinated development of heart and limbs is suggested by a review of human abortus, chromosomal, and teratogenic syndromes, and characterized by an analysis of Mendelian disorders that affect the limbs, heart, or both (672, 202, or 107, respectively). Mendelian syndromes with altered limb patte...

Topics

Embryonic and Fetal Development
Gene Expression Regulation, Developmental
Genetic Variation
Heart Defects, Congenital
Humans
Limb Deformities, Congenital
Syndrome

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