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Article

The cytogenetic theory of the pathogenesis of human adult male germ cell tumors

1 Jan 1998

Abstract excerpt

Human male germ cell tumors (GCTs) represent a biological paradox because, in order to develop into a pluripotential tumor, a germ cell destined to a path of limited or no proliferation must acquire the potential for unlimited proliferation. In addition, it must acquire the ability to elicit embryonal differentiation patterns without the reciprocal inputs from fertilization and the imprinting-associated genomic...

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PMID: 9524565
DOI: 10.1111/j.1699-0463.1998.tb01322.x

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