Article
Developmental transitions in the myosin heavy chain phenotype of human respiratory muscle.
Biology of the neonate - 1 Jan 1996
Lloyd J S, Brozanski B S, Daood M, Watchko J F
Abstract excerpt
We studied the expression of myosin heavy chain (MHC) isoforms in the costal diaphragm (DIA) and the genioglossus (GG) muscles from 16 to 42 weeks gestation in the human using Western blotting techniques. Embryonic/neonatal MHC (MHCemb/neo) was the predominant isoform expressed in the DIA and GG at 16-24 weeks gestation. Subsequently, MHCemb/neo expression declined and the expression of MHCslow and MHC2A...
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