Role of gp41 glycosylation sites in the biological activity of human immunodeficiency virus type 1 envelope glycoprotein.

doi:10.1006/viro.1997.9016

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Article

Role of gp41 glycosylation sites in the biological activity of human immunodeficiency virus type 1 envelope glycoprotein.

Virology - 15 Mar 1998

Perrin C, Fenouillet E, Jones I M

Abstract excerpt

The requirement for glycosylation in the transmembrane protein, gp41, of human immunodeficiency virus type 1 envelope protein for fusion activity has been studied. By using a mutant gene in which three conserved sites have been removed and which shows no fusion ability, genes were constructed whi...

Topics

Animals
CD4-Positive T-Lymphocytes
Chlorocebus aethiops
Giant Cells
Glycosylation
HIV Envelope Protein gp160
HIV Envelope Protein gp41
HeLa Cells
Humans
Mutagenesis
Mutation
Vero Cells
beta-Galactosidase

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