Article
Genotypic and phenotypic characterization of the histoblood group ABO(H) in primary bladder tumors.
International journal of cancer - 16 Mar 1998
Orlow I, Lacombe L, Pellicer I, Rabbani F, Delgado R, Zhang Z F, Szijan I, Cordón-Cardó C
Abstract excerpt
The ABO(H) histoblood group genes have been mapped by linkage analysis to 9q34.1-34.2, an area of common deletions in bladder cancer. Lack of ABO(H) antigen expression in bladder tumors is a frequent and well-documented event. In bladder neoplasms the loss of A and B transferase activity is due t...
Topics
- ABO Blood-Group System
- Antigens, Neoplasm
- Chromosomes, Human, Pair 9
- DNA, Neoplasm
- Gene Expression Regulation, Neoplastic
- Genotype
- Humans
- Loss of Heterozygosity
- Phenotype
- Urinary Bladder
- Urinary Bladder Neoplasms