Cowden syndrome.

Abstract excerpt

Cowden syndrome (CS) is a rare inherited condition characterised by multiple hamartomas in a variety of tissues from all three embryonic layers. It is a cancer predisposition syndrome with an increased risk of developing malignancy in many tissues but especially breast, thyroid and endometrium. It is inherited in an autosomal dominant manner with ∼80% of patients having a germ-line mutation of the PTEN tumour...

Topics

Join the communities discussing this publication.

• Precancerous Conditions
• PTEN Phosphohydrolase
• Risk Assessment
• Thyroid Neoplasms
• Endometrial Neoplasms
• Germ-Line Mutation