Pathology of familial Alzheimer's disease with Lewy bodies.

doi:10.1007/978-3-7091-6846-2_10

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Article

Pathology of familial Alzheimer's disease with Lewy bodies.

Journal of neural transmission. Supplementum - 1 Jan 1997

Revesz T, McLaughlin J L, Rossor M N, Lantos P L

Abstract excerpt

The neuropathological findings of three cases from two pedigrees with early onset familial Alzheimer's disease (FAD) are reported. Affected members of the first family, including cases 1 and 2 reported here, are known to have 717 valine to isoleucine mutation of the amyloid precursor protein (APP...

Topics

Adult
Alzheimer Disease
Amyloid beta-Protein Precursor
Brain
Brain Chemistry
Cytoskeletal Proteins
Female
Humans
Immunohistochemistry
Isoleucine
Lewy Bodies
Male
Middle Aged
Mutation
Neurofibrillary Tangles
Pedigree
Plaque, Amyloid

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