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Article

Oscillating response to a purine nucleotide disrupted by mutation in Paramecium tetraurelia.

The Biochemical journal - 15 Feb 1998

Mimikakis J L, Nelson D L, Preston R R

Abstract excerpt

The purine nucleotide GTP, when added extracellularly, induces oscillations in the swimming behaviour of the protist Paramecium tetraurelia. For periods as long as 10 min the cell swims backwards and forwards repetitively. The oscillations in swimming behaviour are driven by changes in membrane potential of the cell, which in turn are caused by periodic activation of inward Mg2+- and Na+-specific currents. We...

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Identifiers

PMID: 9461502
DOI: 10.1042/bj3300139
PMCID: PMC1219119

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