Article
Inhibition of Mg2+ current by single-gene mutation in Paramecium.
The Journal of membrane biology - 1 May 1994
Preston R R, Kung C
Abstract excerpt
"Eccentric" is a newly-isolated mutant of Paramecium tetraurelia that fails to swim backwards in response to Mg2+. In the wild type, this backward swimming results from Mg2+ influx via a Mg(2+)-specific ion conductance (IMg). Voltage-clamp analysis confirmed that, as suspected, step changes in membrane potential over a physiological range fail to elicit IMg from eccentric. Further electrophysiological...
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