Article
Mouse models of human lysosomal diseases.
Brain pathology (Zurich, Switzerland) - 1 Jan 1998
Suzuki K, Proia R L, Suzuki K
Abstract excerpt
Genetically authentic animal models of human lysosomal diseases occur spontaneously in many mammalian species. However, most are among larger domestic or farm animals with only two well-defined genetic lysosomal diseases known among rodents. This status changed dramatically in recent years with t...
Topics
- Animals
- Disease Models, Animal
- Fabry Disease
- Gangliosidoses
- Gaucher Disease
- Humans
- Lysosomal Storage Diseases
- Mice
- Mice, Knockout
- Niemann-Pick Diseases
- Phenotype