Animal models of lysosomal disease: an overview.

doi:10.1023/a:1005466905180

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Article

Animal models of lysosomal disease: an overview.

Journal of inherited metabolic disease - 1 Aug 1998

Suzuki K, Månsson J E

Abstract excerpt

The relative rarity of human lysosomal disorders, extremely heterogeneous genetic background and ethical restrictions make well-controlled studies difficult with human patients. Genetically authentic animal models complement human patients with their ready availability, homogeneous genetic backgr...

Topics

Animals
Disease Models, Animal
Humans
Lysosomal Storage Diseases
Mice
Mice, Mutant Strains
Phenotype

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