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Article

Promoter and intronic sequences of the human thiopurine S-methyltransferase (TPMT) gene isolated from a human PAC1 genomic library.

Pharmaceutical research - 1 Dec 1997

Krynetski E Y, Fessing M Y, Yates C R, Sun D, Schuetz J D, Evans W E

Abstract excerpt

PURPOSE: To isolate and characterize the polymorphic human thiopurine S-methyltransferase (TPMT) gene. METHODS: The human TPMT gene was isolated by PCR screening of a phage artificial chromosome (PAC) library, using exon- and intron-specific primers, then mapped and sequenced. RESULTS: Two separa...

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Source

Identifiers

PMID: 9453052
DOI: 10.1023/a:1012111325397

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9453052-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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