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Changes in cell-cycle kinetics during the development and evolution of primate neocortex

3 Feb 1998

Abstract excerpt

The evolutionary expansion of neocortical size in mammals is particularly prominent in anthropoid primates (i.e., monkeys, apes, and humans) and reflects an increased number of cortical cells, yet the developmental basis for this increase remains undefined. Cortical cell production depends on the length of the cell-division cycle of progenitor cells during neurogenesis, which previously has been measured only in...

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PMID: 9448316
DOI: 10.1073/pnas.95.3.1242

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