[Analysis of the dependence of the frequency of emergence of His+-reversions in Salmonella typhimurium on the density of the cell population].

Abstract excerpt

The dependence of the appearance of mutants on the number of viable cells plated on a selective medium was analyzed with the spontaneous His+ reversion system in the histidine auxotroph of Salmonella typhimurium strain BA13. The frequency of spontaneous His+ revertants was shown to be inversely proportional to the number of plated cells. Evaluation of residual culture growth on a histidine-deficient medium...

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