Article
Developmental origin and Kit-dependent development of the interstitial cells of cajal in the mammalian small intestine.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 1998
Klüppel M, Huizinga J D, Malysz J, Bernstein A
Abstract excerpt
Interstitial cells of Cajal (ICCs) form a network of cells between the external longitudinal and circular muscle layers at the level of the Auerbach's plexus in the mammalian small intestine. These cells express the Kit receptor tyrosine kinase and are essential for intestinal pacemaker activity....
Topics
- Animals
- Apoptosis
- Digestive System
- Gene Expression Regulation, Developmental
- Intestine, Small
- Mesoderm
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Muscle Contraction
- Muscle, Smooth
- Mutation
- Myosin Heavy Chains
- Proto-Oncogene Proteins c-kit
- RNA, Messenger
- Stem Cells