Genomic sharing surrounding alleles identical by descent: effects of genetic drift and population growth.

doi:10.1002/(SICI)1098-2272(1997)14:6<1125::AID-GEPI94>3.0.CO;2-I

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Article

Genomic sharing surrounding alleles identical by descent: effects of genetic drift and population growth.

Genetic epidemiology - 1 Jan 1997

te Meerman G J, Van der Meulen M A

Abstract excerpt

The number of identical deleterious mutations present in a population may become very large, depending on the combined effect of genetic drift, population growth and limited negative selection. The distribution of the length of the shared area between two random chromosomes carrying the mutations...

Topics

Alleles
Chromosome Mapping
Computer Simulation
Gene Frequency
Genetics, Population
Genome, Human
Homozygote
Humans
Models, Genetic
Mutation

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