Article
[Selection of Bvg- variants of Bordetella pertussis].
Revista Argentina de microbiologia - 1 Jan 2000
Passerini de Rossi B N, Friedman L E, Darnaud S, de Torres R A, Franco M A
Abstract excerpt
Bordetella pertussis virulent strains (Bvg+) produce a wide array of virulence factors. The production of these factors is coordinately regulated by the locus bvg in response to environmental signals in a process known as antigenic modulation. Mutations in the bvg locus originate avirulent variants (Bvg-) that are unable to express virulence factors regardless of growth conditions. In this paper we have obtained...
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