Article
Beta-sarcoglycan: characterization and role in limb-girdle muscular dystrophy linked to 4q12.
Nature genetics - 1 Nov 1995
Lim L E, Duclos F, Broux O, Bourg N, Sunada Y, Allamand V, Meyer J, Richard I, Moomaw C, Slaughter C
Abstract excerpt
beta-Sarcoglycan, a 43 kDa dystrophin-associated glycoprotein, is an integral component of the dystrophin-glycoprotein complex. We have cloned human beta-sarcoglycan cDNA and mapped the beta-sarcoglycan gene to chromosome 4q12. Pericentromeric markers and an intragenic polymorphic CA repeat coseg...
Topics
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 4
- Cloning, Molecular
- Cytoskeletal Proteins
- DNA, Complementary
- Dystroglycans
- Ethnicity
- Humans
- Indiana
- Membrane Glycoproteins
- Molecular Sequence Data
- Muscular Dystrophies
- Mutation
- Sarcoglycans
- Sarcolemma
- Tissue Distribution