Article
lacZ transduction of 9L rat tumor cells without cloning.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 1997
Gabryel-Grudziak A, Boggs S S, Redgate E S, Deutsch M
Abstract excerpt
Several laboratories have introduced the lacZ gene into 9L cells to improve the usefulness of this already popular rat brain tumor model. However, these laboratories were not concerned about possible changes in the phenotypic characteristics of the 9L cell line which can be induced by the selection of lacZ-expressing clones. Here, we describe a method for introducing the lacZ gene into 9L cells without selective...
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