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Article

Rapsyn and agrin slow the metabolic degradation of the acetylcholine receptor.

Molecular and cellular neurosciences - 1 Jan 1997

Phillips W D, Vladeta D, Han H, Noakes P G

Abstract excerpt

Rapsyn is a 43-kDa cytoplasmic protein that clusters nicotinic acetylcholine receptors (AChR) in the postsynaptic membrane. Here we examine the effect of rapsynmediated AChR clustering on the metabolic stability of the AChR. When transfected into QT-6 fibroblasts, cell surface AChRs (alpha, beta, epsilon, and delta subunit combination) pulse labeled with 125I-alpha-bungarotoxin were degraded with a half-life of...

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Identifiers

PMID: 9361285
DOI: 10.1006/mcne.1997.0634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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