Article
The angiotensin-converting enzyme gene and the angiotensin II type I receptor gene as candidate genes for microalbuminuria. A study in nondiabetic and non-insulin-dependent diabetic subjects.
Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 1997
Yudkin J S, Andres C, Mohamed-Ali V, Gould M, Panahloo A, Haines A P, Humphries S, Talmud P
Abstract excerpt
Familial clustering of microalbuminuria with cardiovascular disease suggests a possible common genetic antecedent. We have tested the hypothesis that the angiotensin-converting enzyme (ACE) DD genotype and the angiotensin II type I receptor (AT1R) gene C allele represent the common link between microalbuminuria and coronary heart disease. The frequency of polymorphisms of the ACE and AT1R genes were investigated...
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