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Article

Laboratory diagnosis of central nervous system infections with herpes simplex virus by PCR performed with cerebrospinal fluid specimens.

Journal of clinical microbiology - 1 Nov 1997

Mitchell P S, Espy M J, Smith T F, Toal D R, Rys P N, Berbari E F, Osmon D R, Persing D H

Abstract excerpt

Until recently, the laboratory diagnosis of central nervous system (CNS) infections with herpes simplex virus (HSV) has been limited by poor sensitivity and/or specificity. We assessed the diagnostic utility of PCR for detection of HSV in over 2,100 specimens referred to the Mayo Clinic from August 1993 to May 1996. DNA extracted from cerebrospinal fluid (CSF) samples with IsoQuick was amplified by PCR with...

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Identifiers

PMID: 9350750
DOI: 10.1128/jcm.35.11.2873-2877.1997
PMCID: PMC230078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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