Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modulation of interleukin-6 expression in Hodgkin and Reed-Sternberg cells by Epstein-Barr virus

1 Jul 1997

Abstract excerpt

Variable proportions of Hodgkin's disease (HD) cases are associated with the Epstein-Barr virus (EBV), but the role of EBV in HD is not entirely clear. Hodgkin and Reed-Sternberg (HRS) cells of EBV-associated HD are characterized by expression of the EBV gene product LMP1. In other cellular environments, LMP1 has been shown to induce interleukin (IL)-6. In this study, 105 HD cases were tested for differences in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Eosinophilic Disorders and Syndromes
Share to Lymphoma Diagnosis and Treatment
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9349232
DOI: 10.1002/(sici)1096-9896(199707)182:3<299::aid-path856>3.0.co;2-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modulation of interleukin-6 expression in Hodgkin and Reed-Sternberg cells by Epstein-Barr virusPMID 9349232Read ↗

EBV infection patterns in Hodgkin's disease and normal lymphoid tissue: expression and cellular localization of EBV gene productsSemantic proximity Read ↗

Distinctive expression pattern of the BCL-6 protein in nodular lymphocyte predominance Hodgkin's diseaseSemantic proximity Read ↗

Involvement of Human Herpesvirus-6 Variant B in Classic Hodgkin's Lymphoma via DR7 OncoproteinSemantic proximity Read ↗

Intracellular Signaling Mechanisms and Activities of Human Herpesvirus 8 Interleukin-6Semantic proximity Read ↗

Human Herpesvirus Type 8 Interleukin-6 Homologue Is Functionally Active on Human Myeloma CellsSemantic proximity Read ↗

Human herpesvirus-6 in human lymphomas: identification of specific sequences in Hodgkin's lymphomas by polymerase chain reactionSemantic proximity Read ↗

Detection of interleukin-5 messenger RNA in Reed-Sternberg cells of Hodgkin's disease with eosinophiliaSemantic proximity Read ↗

Distribution and phenotype of Epstein-Barr virus-harboring cells in Hodgkin's disease.Semantic proximity Read ↗

Activation of Epstein-Barr virus replication in Hodgkin and Reed- Sternberg cellsSemantic proximity Read ↗

The nature of Hodgkin and Reed-Sternberg cells, their association with EBV, and their relationship to anaplastic large-cell lymphoma.Semantic proximity Read ↗

Lymphotoxin, tumour necrosis factor and interleukin‐6 gene transcripts are present in Hodgkin and Reed‐Sternberg cells of most Hodgkin's disease casesSemantic proximity Read ↗

Real-Time PCR for Quantification of Human Herpesvirus 6 DNA from Lymph Nodes and SalivaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.