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T Lymphocytes and Macrophages, but Not Motile Spermatozoa, Are a Significant Source of Human Immunodeficiency Virus in Semen

1 Oct 1997

Abstract excerpt

The cellular fraction of semen contains spermatozoa, immature germ cells, leukocytes, and epithelial cells. Recent evidence implicates seminal cells as a major source of sexually transmitted human immunodeficiency virus (HIV) in semen, but the identity and infectious potential of infected cells remains poorly understood. HIV provirus was found in 75% of viable semen cell samples by polymerase chain reaction and...

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PMID: 9333154
DOI: 10.1086/516541

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