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HIV-1 viral DNA is present in ejaculated abnormal spermatozoa of seropositive subjects

14 Sept 2007

Abstract excerpt

BACKGROUND: Semen is the major vehicle for HIV-1 infection as it contains free and cell-associated virions and infected cells. However, the presence of HIV-1 in spermatozoa has been a matter of debate, since the sperm cell fraction may contain somatic infected cells that jeopardize the attribution of the detected virus to the spermatozoa. METHODS: Spermatozoa from 12 HIV-1 seropositive subjects were purified by...

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PMID: 17855413
DOI: 10.1093/humrep/dem288

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