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Article

Detection of HIV-1 proviral DNA in sperm from HIV-1-infected men

1 Dec 1994

Abstract excerpt

OBJECTIVE: Sexual transmission is a major mode of the spread of HIV-1, although the cellular and molecular mechanisms are poorly defined. In this study, we sought to assess the cellular reservoirs of HIV-1 proviral DNA in the semen of HIV-1-infected men. DESIGN AND METHODS: An in situ polymerase chain reaction (IS-PCR), which amplifies specific genes within intact cells, was used to evaluate levels of HIV-1...

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PMID: 7888115
DOI: 10.1097/00002030-199412000-00005

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