Article
Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors: definition of phenotypic groups.
Cancer research - 1 Oct 1997
Courjal F, Cuny M, Simony-Lafontaine J, Louason G, Speiser P, Zeillinger R, Rodriguez C, Theillet C
Abstract excerpt
DNA amplification is frequent in breast cancer and has been associated with specific clinicopathological parameters and/or worsened course of the disease. In the present work, we were interested in further defining the association linking the occurrence of DNA amplification to the emergence of sp...
Topics
- Adult
- Aged
- Blotting, Southern
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Carcinoma, Lobular
- Chromosome Mapping
- Chromosomes, Human
- DNA Probes
- DNA, Neoplasm
- Estrogens
- Female
- Gene Amplification
- Genes, myc
- Genetic Markers
- Humans
- Middle Aged
- Neoplasm Invasiveness