Two different connexin 26 mutations in an inbred kindred segregating non-syndromic recessive deafness: implications for genetic studies in isolated populations.

doi:10.1093/hmg/6.12.2163

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Article

Two different connexin 26 mutations in an inbred kindred segregating non-syndromic recessive deafness: implications for genetic studies in isolated populations.

Human molecular genetics - 1 Nov 1997

Carrasquillo M M, Zlotogora J, Barges S, Chakravarti A

Abstract excerpt

Non-syndromic recessive deafness (NSRD) is the most common form of prelingual hereditary hearing loss. To date, 10 autosomal NSRD loci (DFNBs) have been identified by genetic mapping; at least three times as many additional loci are expected to be identified. We have performed linkage analyses in...

Topics

Chromosomes, Human, Pair 13
Connexin 26
Connexins
Consanguinity
Deafness
Genetic Linkage
Haplotypes
Humans
Mutation
Pedigree

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