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Article

Biochemical and genetic studies in a family with mitochondrial myopathy.

Muscle & nerve - 1 Oct 1997

Heiman-Patterson T D, Argov Z, Chavin J M, Kalman B, Alder H, DiMauro S, Bank W, Tahmoush A J

Abstract excerpt

We present a family with severe exercise intolerance, progressive proximal weakness, and lactic acidemia. Fifteen of 24 family members in five generations were affected. Since the affected males do not have offspring at this time, the family pedigree is consistent with either maternal or autosomal dominant inheritance. Muscle histochemistry showed ragged-red fibers and electron microscopy showed globular...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9324076
DOI: 10.1002/(sici)1097-4598(199710)20:10<1219::aid-mus2>3.0.co;2-f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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