Article
S-adenosil-L-methionine is able to reverse the immunosuppressive effects of chenodeoxycholic acid in vitro.
International journal of immunopharmacology - 1 Mar 1997
Filaci G, Pelli N, Sacco T, Contini P, Lanza L, Picciotto A, Scudeletti M, Puppo F, Castiglioni G, Indiveri F
Abstract excerpt
The study was conceived to evaluate if S-adenosil-L-methionine, a substance commonly used in the treatment of cholestasis in patients with cirrhosis and chronic hepatitis, exerts any immunological effect and of it is able to counterbalance bile acid-mediated immunosuppression. Proliferation and interleukin 2 and interferon-gamma secretion of human lymphocytes, collected from healthy subjects and exposed to...
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