Article
Factor V Leiden and other coagulation factor mutations affecting thrombotic risk.
Clinical chemistry - 1 Sept 1997
Bertina R M
Abstract excerpt
Five genetic defects have been established as risk factors for venous thrombosis. Three are protein C, protein S, and antithrombin deficiencies, defects in the anticoagulant pathways of blood coagulation. Together they can be found in approximately 15% of families with inherited thrombophilia. Th...
Topics
- Base Sequence
- Blood Coagulation Factors
- Clinical Laboratory Techniques
- Factor V
- Humans
- Mutation
- Protein C
- Protein C Deficiency
- Protein S Deficiency
- Prothrombin
- Risk Factors
- Thrombophlebitis
- Thrombosis