Article
Donor factor V Leiden mutation and vascular thrombosis following liver transplantation.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Jan 1998
Hirshfield G, Collier J D, Brown K, Taylor C, Frick T, Baglin T P, Alexander G J
Abstract excerpt
The most commonly detected hypercoagulable state involves an abnormal factor V protein synthesized by the liver in which arginine at position 506 is replaced by glutamine as a result of a single-point mutation in the factor V gene (factor V Leiden). Liver transplantation is complicated by hepatic vascular thrombosis in up to 15% of cases, resulting in graft loss in most instances. This retrospective study...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.