Article
Donor factor V Leiden mutation and vascular thrombosis following liver transplantation.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Jan 1998
Hirshfield G, Collier J D, Brown K, Taylor C, Frick T, Baglin T P, Alexander G J
Abstract excerpt
The most commonly detected hypercoagulable state involves an abnormal factor V protein synthesized by the liver in which arginine at position 506 is replaced by glutamine as a result of a single-point mutation in the factor V gene (factor V Leiden). Liver transplantation is complicated by hepatic...
Topics
- Adolescent
- Adult
- Aged
- DNA
- Factor V
- Female
- Humans
- Liver Transplantation
- Male
- Middle Aged
- Mutation
- Retrospective Studies
- Risk Factors
- Thrombosis