Article
Mutation-selection balance under genomic imprinting at an autosomal locus.
Genetics - 1 Sept 1997
Spencer H G
Abstract excerpt
I model the effect of genomic imprinting on the equilibrium allele frequencies at an autosomal diallelic locus subject to viability selection and mutation. The population size is assumed to be very large; male and female mutation rates may be unequal. Different models examine cases of the inactivation of one gene (with both complete and partial penetrance) and of differential expression of genes according to the...
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