Article
On the origin and frequency of Y chromosome deletions responsible for severe male infertility
1 Jul 1997
Abstract excerpt
The origin of deletions associated with non-obstructive severe oligozoospermia in men are discussed. Deletions could arise during various stages of meiosis, at later stages in spermatids, or post-fertilization. Certain embryonic stages may be highly sensitive. The possibilities of an inherited propensity to these and other deletions, and of mosaicism in embryos are assessed.
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