Article
High frequency of well-defined Y-chromosome deletions in idiopathic Sertoli cell-only syndrome.
Human reproduction (Oxford, England) - 1 Feb 1998
Foresta C, Ferlin A, Garolla A, Moro E, Pistorello M, Barbaux S, Rossato M
Abstract excerpt
Idiopathic Sertoli cell-only syndrome (SCOS) is characterized by azoospermia, small testes, absence of germ cells in the testes, elevated follicle stimulating hormone and normal testosterone concentrations. The Y-chromosome is involved in the regulation of spermatogenesis and in the pathogenesis of a fraction of idiopathic male infertility. An azoospermia factor (AZF) is present on the Y-chromosome long arm...
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