Article
Studies of the genetic variability of the coding region of the hepatocyte nuclear factor-4alpha in Caucasians with maturity onset NIDDM.
Diabetologia - 1 Aug 1997
Møller A M, Urhammer S A, Dalgaard L T, Reneland R, Berglund L, Hansen T, Clausen J O, Lithell H, Pedersen O
Abstract excerpt
Mutations in the hepatocyte nuclear factor-4alpha (HNF-4alpha) gene cause the type 1 form of maturity onset diabetes of the young (MODY1). To address the question of whether genetic variability of HNF-4alpha is associated with late onset non-insulin-dependent diabetes mellitus (NIDDM) we have sequenced the coding region and intron/exon boundaries of the gene in 36 randomly recruited Danish NIDDM patients. Two...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
