Article
Oestrogen receptor gene polymorphisms and ovarian stimulation for in-vitro fertilization.
Human reproduction (Oxford, England) - 1 Jul 1997
Georgiou I, Konstantelli M, Syrrou M, Messinis I E, Lolis D E
Abstract excerpt
Experimental evidence has shown that mice lacking the oestrogen receptor (ESR) gene are infertile with cystic ovaries and follicular arrest. In humans, several polymorphisms and mutations in the ESR gene have been identified. In this study we have analysed a common PvuII and a rare BstUI polymorphism in the ESR gene. Analysis was carried out on DNA samples from women undergoing ovarian stimulation for in-vitro...
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