Article
Asp905Tyr polymorphism of protein phosphatase 1 G subunit gene in hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Aug 1997
Shen G Q, Ikegami H, Fujisawa T, Hamada Y, Kamide K, Rakugi H, Higaki J, Murakami H, Shimamoto K, Ogihara T
Abstract excerpt
A possible pathogenic polymorphism in the gene for the G subunit of the glycogen-associated regulatory form of protein phosphatase 1 (PP1 G subunit), causing an Asp-to-Tyr substitution at codon 905 (Asp905Tyr), has been reported to be associated with insulin resistance and hypersecretion of insul...
Topics
- Aged
- Amino Acid Sequence
- Female
- Gene Frequency
- Genotype
- Humans
- Hypertension
- Insulin Resistance
- Isoenzymes
- Male
- Middle Aged
- Molecular Sequence Data
- Phosphoprotein Phosphatases
- Polymorphism, Genetic
- Protein Phosphatase 1