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Article

Permeability and residual plasma volume of human, Dutch variant, and rat amyloid beta-protein 1-40 at the blood-brain barrier.

Neurobiology of disease - 1 Jan 1997

Poduslo J F, Curran G L, Haggard J J, Biere A L, Selkoe D J

Abstract excerpt

The permeability of normal human, the human Dutch variant, and the rat A beta 1-40 proteins at the blood-brain barrier (BBB) was determined in the normal adult rat by quantifying the permeability coefficient-surface area (PS) product for each protein after correction for the residual plasma volume (Vp) occupied by the protein in the blood vessels of different brain regions. The PS for normal and Dutch A beta...

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PMID: 9258909
DOI: 10.1006/nbdi.1997.0132

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