Article
Permeability and residual plasma volume of human, Dutch variant, and rat amyloid beta-protein 1-40 at the blood-brain barrier.
Neurobiology of disease - 1 Jan 1997
Poduslo J F, Curran G L, Haggard J J, Biere A L, Selkoe D J
Abstract excerpt
The permeability of normal human, the human Dutch variant, and the rat A beta 1-40 proteins at the blood-brain barrier (BBB) was determined in the normal adult rat by quantifying the permeability coefficient-surface area (PS) product for each protein after correction for the residual plasma volum...
Topics
- Amino Acid Sequence
- Amyloid beta-Peptides
- Animals
- Blood-Brain Barrier
- Brain
- Capillary Permeability
- Genetic Variation
- Half-Life
- Humans
- Insulin
- Iodine Radioisotopes
- Molecular Sequence Data
- Peptide Fragments
- Plasma Volume
- Rats
- Rats, Sprague-Dawley
- Tissue Distribution