Article
Thrombophilia as a multigenic disease.
Haematologica - 1 Jan 1999
Zöller B, García de Frutos P, Hillarp A, Dahlbäck B
Abstract excerpt
BACKGROUND AND OBJECTIVE: Venous thrombosis is a common disease annually affecting 1 in 1000 individuals. The multifactorial nature of the disease is illustrated by the frequent identification of one or more predisposing genetic and/or environmental risk factors in thrombosis patients. Most of the genetic defects known today affect the function of the natural anticoagulant pathways and in particular the protein C...
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